If you can afford this device, somehow, get it. I have PMDD and to say my mood swings are now night and day (almost not there during luteal) is shocking even to write. Use it every day in... Ver mais
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If you can afford this device, somehow, get it. I have PMDD and to say my mood swings are now night and day (almost not there during luteal) is shocking even to write. Use it every day in... Ver mais
A empresa respondeu
I’ve just finished the second cycle with Nettle, and OH MY GOD?! I don’t remember the last time when I’ve had energy through the whole month and not just the first 10 days of the cycle. There were st... Ver mais
A empresa respondeu
I had a full hysterectomy several years ago. So I can't speak on how well Lutea works on menstrual. But as for the mental brain fog and anxiety issues it has helped greatly. I feel calmer and able to... Ver mais
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The Nettle has been life changing as someone with pcos and pmdd, and long term depression. It’s helped me to manage my mood and reduced my pain symptoms. It’s not like any other treatment I have exper... Ver mais
A empresa respondeu
Samphire Neuroscience is a neurotechnology company dedicated to maximizing the wellbeing of women by delivering pioneering neurotechnology and evidence-based solutions that are drug and hormone-free. Our products include Nettle™, a medically-approved brain stimulation device to tackle PMS and menstrual pain non-invasively, Lutea™, a wellness brain stimulation device to support women during hormonally challenging moments, and the Samphire App, which helps women understand the patterns behind their cycles.
85 Great Portland Street, W1W 7LT, London, Reino Unido
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I work in women’s and mental health and using nettle has had the most significant impact on my PMDD related depression out of all other interventions I have tried. It is now something I recommend to clients. The team are always very responsive with any queries.

Resposta da Samphire Neuroscience
Nettle really helps me every month, and even knowing it's there as a tool for me makes a big difference. Sessions lift my mood and help me feel more in control of my mood and emotions. I've had it since September 25. The customer service is brilliant and I truly believe Samphire will be everywhere in 5 years, changing the game for even more women

Resposta da Samphire Neuroscience
Nettle helps me with my PMDS symptoms and makes everyday life much easier. Before Nettle, I was taking SSRIs, and on really bad days I would occasionally need a calming medication. Overall, I feel like I can control my emotions a little better now. There are fewer extremely bad days.
I use Nettle from ovulation until my period, so for quite a lot of days each month. At the beginning, I had an issue with the device, but the support team was very quick and truly excellent. I received a replacement right away and got immediate help.
Thank you for this wonderful invention! Nettle doesn’t cure my PMDS, but even the fact that it helps a little brings me so much relief. Thank you!

Resposta da Samphire Neuroscience
The Nettle has been life changing as someone with pcos and pmdd, and long term depression. It’s helped me to manage my mood and reduced my pain symptoms. It’s not like any other treatment I have experienced, with almost immediate lessening of my anxiety. After 9 months of use, I swear by it. It makes bad days much brighter and more manageable. I am so grateful to be able to experience this after years of struggling deeply. Thanks to the whole team. Great customer service too!

Resposta da Samphire Neuroscience
I've been using Nettle since May 2025, and it's given me real, felt relief from some of the psychological symptoms of my PMDD including anxiety, overwhelm, panic. The team is also amazingly responsive to questions/queries/feedback

Resposta da Samphire Neuroscience
Less crying, less snapping, just in general a more calm time before my periods. Between loosing weight and pre-menopause, my cycle has become notable longer than it used to be, and I'm so grateful that I don't have to spend that time waiting for my period and the calmer, more positive part of my cycle to begin. Or dreading the luteal phase, when my mood would start to dive.

Resposta da Samphire Neuroscience
I found Nettle on a Reddit page. Someone had mentioned a medical trial for PMDD and I was desperate. I was spending half of my month, every month unable to function as a human. I play several sports that require concentration to put it mildly, and I was actually refusing to do them for half of the month because it would end in screaming, tears or suicidal thoughts. I had really got to the end of my tether! I knew the doctors were going to be less than helpful, I didn't want to go down the SSRI or contraceptive route and had already been told a firm no on any permanent surgical solutions.
Nettle has somewhat changed my life! I was sceptical at first, the reviews almost seemed too good to be true but after 3 months (the first two believing it wasn't going to work and it was all a big lie) the changes have been nothing short of a miracle. I still have the odd day where I feel down or angry/irritable, but I am able to acknowledge this and walk away from the situation and start again. I now forget that I have booked competitions and leisure activities on my 'bad' days as they don't cause an issue.
Subsequently, after the medical trial I bought myself my own device and I haven't looked back since. If anyone is looking for an alternative that doesn't include years of being passed around doctor to doctor, just do it! With a money back trial too, what is there to lose in my opinion.

Resposta da Samphire Neuroscience
This is my first month using Nettle and already this cycle my luteal phase has been completely different. My PMDD Symptoms are practically nonexistent and hopefully it will help with endo pain as well. Will update to share results. I am amazed with Nettle!

Resposta da Samphire Neuroscience
I’ve been using Nettle since it launched and it’s made such a noticeable difference in my pms and pmdd symptoms. I used to have at least 2-3 days every month where I couldn’t function, either due to complete exhaustion, fatigue and anxiety or period pain in the first day of my cycle. With Nettle my body feels much more comfortable overall. My energy levels are sustained, I’m feeling more in control emotionally (not 100%) and the cramping is so much milder that I do not feel I need to take a pain killer anymore or lay down for a nap. Using Nettle allows me to feel more normal during my period and not to miss out on life.

Resposta da Samphire Neuroscience
The Nettle from Samphire has been a great addition to my PMDD protocol, I was one of the first batches and the customer service from the founder and her team was quick and efficient. As one of the first batches I got a lemon and it was dealt with quickly. I used it for months consistently and noticed a mood improvement which is such small statement but profound when PMDD disables your normal life. supporting a women led company is always a plus

Resposta da Samphire Neuroscience
This company truly cares about women's health. Communication has been excellent from pre-purchase to support afterwards as a US customer. I've been using Nettle for 5 months now. Usually I have a sharp transition from ovulation to luteal phase with a drop in mood and onset of physical symptoms with almost 2 weeks of challenging days. While I haven't noticed a dramatic difference, I feel like I now have one to two days back per month and a smoother transition, which is actually a big deal. More importantly, just having another tool in my toolbelt and knowing research is being done on PMS and PMDD feels so good. I almost cried the first time I needed support on a rough day and found a category of luteal phase meditation on the Samphire app. I felt so SEEN.
A few things I wish I knew- as a US customer I needed an adapter for Nettle (but I purchased before the US version as available so that might be why). There is a subscription for the app, and you will need to get refills for sponges every 3 months or so but they are free or affordable if you go through them more quickly. Pro tip- run a session after you've washed your hair, it's much easier to get a strong connection!

Resposta da Samphire Neuroscience
I have been using Nettle for 4-6 months and I feel very happy with it. I don’t know yet if it’s helping my mood, reactivity, lability, etc., yet! I know that I don’t mind the relaxing and mindful time I get 5 times a month after I shower. I have enjoyed and learned a lot from Emilé’s talks on pms and pmdd. Thank you Nettle and excited to keep trying. The app is good too.

Resposta da Samphire Neuroscience
First of all, there is an incredible team behind Nettle — genuinely caring, responsive, and always willing to help. Every question I had was answered with clarity, understanding, and kindness, and the support works at an almost unbelievable speed.
I have been using Nettle for about a year now, and I can truly say it has helped me — a lot — to live a much better quality of life. I have suffered from very painful periods my entire life, and about seven years ago severe PMS symptoms were added to that — intense irritability, emotional overwhelm, and yes, an unstoppable craving for chocolate. I understood that it was PMS, but I had absolutely no tools to work with my emotions.
On top of that, during PMS I was often unable to work for around 7–10 days each month. Then my period itself would last about 5 days, and suddenly I realized that in a 27-day cycle I only had about one “normal” week. This had a huge impact on both my work and overall quality of life.
When I discovered Emilie and learned that she was creating something new, I was one of the very first people to try Nettle. Since then, my PMS has improved dramatically. I no longer feel uncontrollably angry or emotionally overwhelmed, and most importantly — I am functional, productive, and have energy. The menstrual pain that used to be unbearable has significantly decreased. I still take pain medication because the pain is not completely gone, but now it is manageable and the medication works within 15–20 minutes. Before, it often didn’t work at all, leaving me in pain with no options left.
I truly and wholeheartedly recommend this device, because it has genuinely helped me.
I did experience some challenges with the device itself — it sometimes charged very slowly and occasionally wouldn’t charge at all. Eventually, one day it stopped charging completely and appeared to malfunction. However, the support team reacted immediately and wonderfully, and a replacement Nettle is already on its way to me. This level of care and responsibility only strengthens my trust in the brand.

Resposta da Samphire Neuroscience
Nettle is a revolutionary device for taking back the responsabilitues of our health. It s wonderfull to manage ans schedule a session with nettle the moment u need it.
It is very efficient because we can act daily on our pain and discomfort.

Resposta da Samphire Neuroscience
I’ve used nettle for a year now and have noticed a significant difference in my symptoms during my luteal phase. App is easy to use and helpful to track my symptoms !

Resposta da Samphire Neuroscience
nettle has been such a great addition to my PMDD treatment, truly not much actually works and especially not without side effects. my nettle (while absolutely not 100% effective), takes the edge off to a more manageable level and is really easy to keep up with as part of my routine. also reduces my cramps a bit which I honestly wasn’t expecting at all! i love that this is a women’s team too, our health is so under-researched, and everyone from samphire has been incredibly responsive when I’ve needed it. looking forward to seeing how this continues to develop!

Resposta da Samphire Neuroscience
Fantastic customer service, first of all. I had some questions and immediately got answers from Em. It helped so much as I was overwhelmed at first and was scared to do something wrong, but she went through it all with me and I felt so much more confident using it. I have only recently started using the Nettle regularly (after setting up notifications in the app so it reminds me when I need to use it), so I can’t say just yet how much it’s improving my symptoms of PMDD moods and Endometriosis pain, but after being offered the only treatment option of chemically induced menopause by nhs, and declining that, I’m just so happy to have this device as alternative treatment for these very overlooked and underesearched conditions. I’m very hopeful it will help because there are so many positive reviews and Em is very knowledgeable on these conditions. The device is comfortable and easy to use. Once you’ve used it a few times it becomes second nature to go through the steps. It tingles and itches a bit at first but that only lasts a minute for me and then it’s unnoticeable! I can’t wait to see how this device helps me.

Resposta da Samphire Neuroscience
Nettle is a game changer.
I've had it for a year now and it has helped massively with my PMDD. I find it extremely helpful around 10-7 days before my cycle when I feel the most erratic. The feeling when your mind is racing is tuned down almost instantly after using it and I can think in single sentences again.
It helps with endo in reducing the amount of painkillers I take, but I am not really very consistent with it due to my lifestyle/job. I could probably get better results being more consistent.

Resposta da Samphire Neuroscience
Using Nettle has been a life saver. I use it on days that my symptoms flare, which for me can also be around ovulation. I can feel relief midway through a session sometimes. It has eased cramps and pain, and mostly been incredible for my mood. It has taken the edge off when I’m really spiraling and has brought me back into a regulated state from a very depressed and overwrought place. I have had less suicidal ideation since using it, and when I did feel it, the Nettle device helped bring my thinking back down into a safe place. I’m very thankful and grateful that it exists.
If you are on the fence (like I was because I was a bit worried about messing with my brain) I would highly recommend trying it because it has improved my life and given me a tool. Before I felt alone in dealing with PMDD, even when consulting professionals. I tried therapy, diet changes, birth control, SSRIs, and supplements. Nettle has done more for me than any of the other interventions I’ve tried and in a faster period of time.
Also Samphire seems like a wonderful company. Their customer service is stellar and responsive. They really care about women’s health and want to improve lives. The app is lovely and I now use that to track everything and am getting better data about my cycle and trends.

Resposta da Samphire Neuroscience
Samphire has been a very supportive company to work with! Any time I've had questions they've responded quickly. And I do think my Nettle does help with my PMDD.

Resposta da Samphire Neuroscience
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